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Impaired Ethanol-Induced Sensitization and Decreased Cannabinoid Receptor-1 in a Model of Posttraumatic Stress Disorder

BACKGROUND AND PURPOSE: Impaired striatal neuroplasticity may underlie increased alcoholism documented in those with posttraumatic stress disorder (PTSD). Cannabinoid receptor-1 (CB1) is sensitive to the effects of ethanol (EtOH) and traumatic stress, and is a critical regulator of striatal plastici...

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Detalles Bibliográficos
Autores principales: Matchynski-Franks, Jessica J., Susick, Laura L., Schneider, Brandy L., Perrine, Shane A., Conti, Alana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871361/
https://www.ncbi.nlm.nih.gov/pubmed/27186643
http://dx.doi.org/10.1371/journal.pone.0155759