Genetic Deletion of the Clathrin Adaptor GGA3 Reduces Anxiety and Alters GABAergic Transmission

Golgi-localized γ-ear-containing ARF binding protein 3 (GGA3) is a monomeric clathrin adaptor that has been shown to regulate the trafficking of the Beta-site APP-cleaving enzyme (BACE1), which is required for production of the Alzheimer’s disease (AD)-associated amyloid βpeptide. Our previous studi...

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Detalles Bibliográficos
Autores principales: Walker, Kendall R., Modgil, Amit, Albrecht, David, Lomoio, Selene, Haydon, Philip G., Moss, Stephen J., Tesco, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871427/
https://www.ncbi.nlm.nih.gov/pubmed/27192432
http://dx.doi.org/10.1371/journal.pone.0155799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871427/
https://www.ncbi.nlm.nih.gov/pubmed/27192432
http://dx.doi.org/10.1371/journal.pone.0155799

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