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Longitudinal Changes in the Motor Learning-Related Brain Activation Response in Presymptomatic Huntington's Disease

Neurocognitive decline, including deficits in motor learning, occurs in the presymptomatic phase of Huntington’s disease (HD) and precedes the onset of motor symptoms. Findings from recent neuroimaging studies have linked these deficits to alterations in fronto-striatal and fronto-parietal brain net...

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Detalles Bibliográficos
Autores principales: Holtbernd, Florian, Tang, Chris C., Feigin, Andrew, Dhawan, Vijay, Ghilardi, Maria Felice, Paulsen, Jane S., Guttman, Mark, Eidelberg, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871440/
https://www.ncbi.nlm.nih.gov/pubmed/27192167
http://dx.doi.org/10.1371/journal.pone.0154742