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Both Complexity and Location of DNA Damage Contribute to Cellular Senescence Induced by Ionizing Radiation

Persistent DNA damage is considered as a main cause of cellular senescence induced by ionizing radiation. However, the molecular bases of the DNA damage and their contribution to cellular senescence are not completely clear. In this study, we found that both heavy ions and X-rays induced senescence...

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Detalles Bibliográficos
Autores principales: Zhang, Xurui, Ye, Caiyong, Sun, Fang, Wei, Wenjun, Hu, Burong, Wang, Jufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871470/
https://www.ncbi.nlm.nih.gov/pubmed/27187621
http://dx.doi.org/10.1371/journal.pone.0155725