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Ferulic Acid Administered at Various Time Points Protects against Cerebral Infarction by Activating p38 MAPK/p90RSK/CREB/Bcl-2 Anti-Apoptotic Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion Injury in Rats

OBJECTIVES: This study aimed to evaluate the effects of ferulic acid (FA) administered at various time points before or after 30 min of middle cerebral artery occlusion (MCAo) followed by 7 d of reperfusion and to examine the involvement of mitogen-activated protein kinase (MAPK) signaling pathways...

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Detalles Bibliográficos
Autores principales: Cheng, Chin-Yi, Tang, Nou-Ying, Kao, Shung-Te, Hsieh, Ching-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871485/
https://www.ncbi.nlm.nih.gov/pubmed/27187745
http://dx.doi.org/10.1371/journal.pone.0155748