Low Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines

Due to advances in sequencing technology, somatically mutated cancer antigens, or neoantigens, are now readily identifiable and have become compelling targets for immunotherapy. In particular, neoantigen-targeted vaccines have shown promise in several pre-clinical and clinical studies. However, to d...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Spencer D., Brown, Scott D., Wick, Darin A., Nielsen, Julie S., Kroeger, David R., Twumasi-Boateng, Kwame, Holt, Robert A., Nelson, Brad H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871527/
https://www.ncbi.nlm.nih.gov/pubmed/27192170
http://dx.doi.org/10.1371/journal.pone.0155189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871527/
https://www.ncbi.nlm.nih.gov/pubmed/27192170
http://dx.doi.org/10.1371/journal.pone.0155189

Ejemplares similares