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Wnt Signaling Alteration in the Spinal Cord of Amyotrophic Lateral Sclerosis Transgenic Mice: Special Focus on Frizzled-5 Cellular Expression Pattern

BACKGROUND: Amyotrophic lateral sclerosis is a chronic neurodegenerative disease characterized by progressive paralysis due to degeneration of motor neurons by unknown causes. Recent evidence shows that Wnt signaling is involved in neurodegenerative processes, including Amyotrophic Lateral Sclerosis...

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Detalles Bibliográficos
Autores principales: González-Fernández, Carlos, Mancuso, Renzo, del Valle, Jaume, Navarro, Xavier, Rodríguez, Francisco Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871528/
https://www.ncbi.nlm.nih.gov/pubmed/27192435
http://dx.doi.org/10.1371/journal.pone.0155867