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The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles

The dense-core vesicle is a secretory organelle that mediates the regulated release of peptide hormones, growth factors, and biogenic amines. Dense-core vesicles originate from the trans-Golgi of neurons and neuroendocrine cells, but it is unclear how this specialized organelle is formed and acquire...

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Detalles Bibliográficos
Autores principales: Topalidou, Irini, Cattin-Ortolá, Jérôme, Pappas, Andrea L., Cooper, Kirsten, Merrihew, Gennifer E., MacCoss, Michael J., Ailion, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871572/
https://www.ncbi.nlm.nih.gov/pubmed/27191843
http://dx.doi.org/10.1371/journal.pgen.1006074