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The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles
The dense-core vesicle is a secretory organelle that mediates the regulated release of peptide hormones, growth factors, and biogenic amines. Dense-core vesicles originate from the trans-Golgi of neurons and neuroendocrine cells, but it is unclear how this specialized organelle is formed and acquire...
Autores principales: | Topalidou, Irini, Cattin-Ortolá, Jérôme, Pappas, Andrea L., Cooper, Kirsten, Merrihew, Gennifer E., MacCoss, Michael J., Ailion, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871572/ https://www.ncbi.nlm.nih.gov/pubmed/27191843 http://dx.doi.org/10.1371/journal.pgen.1006074 |
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