PEGylation of Truncated Streptokinase Leads to Formulation of a Useful Drug with Ameliorated Attributes

Streptokinase (SK) remains a favored thrombolytic agent in the developing world as compared to the nearly 10-fold more expensive human tissue-plasminogen activator (tPA) for the dissolution of pathological fibrin clots in myocardial infarction. However, unlike the latter, SK induces systemic activat...

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Detalles Bibliográficos
Autores principales: Sawhney, Pooja, Katare, Keya, Sahni, Girish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871584/
https://www.ncbi.nlm.nih.gov/pubmed/27192220
http://dx.doi.org/10.1371/journal.pone.0155831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871584/
https://www.ncbi.nlm.nih.gov/pubmed/27192220
http://dx.doi.org/10.1371/journal.pone.0155831

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