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PEGylation of Truncated Streptokinase Leads to Formulation of a Useful Drug with Ameliorated Attributes
Streptokinase (SK) remains a favored thrombolytic agent in the developing world as compared to the nearly 10-fold more expensive human tissue-plasminogen activator (tPA) for the dissolution of pathological fibrin clots in myocardial infarction. However, unlike the latter, SK induces systemic activat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871584/ https://www.ncbi.nlm.nih.gov/pubmed/27192220 http://dx.doi.org/10.1371/journal.pone.0155831 |