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Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus

Aspergillus fumigatus is the most prevalent airborne fungal pathogen causing invasive fungal infections in immunosuppressed individuals. The histidine biosynthetic pathway is found in bacteria, archaebacteria, lower eukaryotes, and plants, but is absent in mammals. Here we demonstrate that deletion...

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Detalles Bibliográficos
Autores principales: Dietl, Anna-Maria, Amich, Jorge, Leal, Sixto, Beckmann, Nicola, Binder, Ulrike, Beilhack, Andreas, Pearlman, Eric, Haas, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871644/
https://www.ncbi.nlm.nih.gov/pubmed/26854126
http://dx.doi.org/10.1080/21505594.2016.1146848