Decoding Polo-like kinase 1 signaling along the kinetochore-centromere axis

Protein kinase signaling along the kinetochore-centromere axis is crucial to assure mitotic fidelity, yet its spatial coordination is obscure. Here, we examined how pools of human Polo-like kinase 1 (Plk1) within this axis control signaling events to elicit mitotic functions. To do this, we restrict...

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Detalles Bibliográficos
Autores principales: Lera, Robert F., Potts, Gregory K., Suzuki, Aussie, Johnson, James M., Salmon, Edward D., Coon, Joshua J., Burkard, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871769/
https://www.ncbi.nlm.nih.gov/pubmed/27043190
http://dx.doi.org/10.1038/nchembio.2060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871769/
https://www.ncbi.nlm.nih.gov/pubmed/27043190
http://dx.doi.org/10.1038/nchembio.2060

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