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Decoding Polo-like kinase 1 signaling along the kinetochore-centromere axis
Protein kinase signaling along the kinetochore-centromere axis is crucial to assure mitotic fidelity, yet its spatial coordination is obscure. Here, we examined how pools of human Polo-like kinase 1 (Plk1) within this axis control signaling events to elicit mitotic functions. To do this, we restrict...
Autores principales: | Lera, Robert F., Potts, Gregory K., Suzuki, Aussie, Johnson, James M., Salmon, Edward D., Coon, Joshua J., Burkard, Mark E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871769/ https://www.ncbi.nlm.nih.gov/pubmed/27043190 http://dx.doi.org/10.1038/nchembio.2060 |
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