Click-electron microscopy for imaging metabolically tagged non-protein biomolecules

Electron microscopy (EM) has long been the main technique to image cell structures with nanometer resolution, but has lagged behind light microscopy in the crucial ability to make specific molecules stand out. Here we introduce “Click-EM,” a labeling technique for correlative light microscopy and EM...

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Detalles Bibliográficos
Autores principales: Ngo, John T., Adams, Stephen R., Deerinck, Thomas J., Boassa, Daniela, Rodriguez-Rivera, Frances, Palida, Sakina F., Bertozzi, Carolyn R., Ellisman, Mark H., Tsien, Roger Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871776/
https://www.ncbi.nlm.nih.gov/pubmed/27110681
http://dx.doi.org/10.1038/nchembio.2076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871776/
https://www.ncbi.nlm.nih.gov/pubmed/27110681
http://dx.doi.org/10.1038/nchembio.2076

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