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Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103(+) dendritic cells

Tolerance to harmless exogenous antigens is the default immune response in the gastrointestinal tract. Although extensive studies have demonstrated the importance of the mesenteric lymph nodes (MLN) and intestinal CD103(+) dendritic cells (DCs) in driving small intestinal tolerance to protein antige...

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Detalles Bibliográficos
Autores principales: Veenbergen, Sharon, van Berkel, Lisette A, du Pré, M Fleur, He, JianPing, Karrich, Julien J, Costes, Léa MM, Luk, Franka, Simons-Oosterhuis, Ytje, Raatgeep, Rolien HC, Cerovic, Vuk, Cupedo, Tom, McI Mowat, Allan, Kelsall, Brian L, Samsom, Janneke N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871788/
https://www.ncbi.nlm.nih.gov/pubmed/26577569
http://dx.doi.org/10.1038/mi.2015.118