Cargando…
Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103(+) dendritic cells
Tolerance to harmless exogenous antigens is the default immune response in the gastrointestinal tract. Although extensive studies have demonstrated the importance of the mesenteric lymph nodes (MLN) and intestinal CD103(+) dendritic cells (DCs) in driving small intestinal tolerance to protein antige...
Autores principales: | Veenbergen, Sharon, van Berkel, Lisette A, du Pré, M Fleur, He, JianPing, Karrich, Julien J, Costes, Léa MM, Luk, Franka, Simons-Oosterhuis, Ytje, Raatgeep, Rolien HC, Cerovic, Vuk, Cupedo, Tom, McI Mowat, Allan, Kelsall, Brian L, Samsom, Janneke N |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871788/ https://www.ncbi.nlm.nih.gov/pubmed/26577569 http://dx.doi.org/10.1038/mi.2015.118 |
Ejemplares similares
-
IL-10 signaling in dendritic cells controls IL-1β-mediated IFNγ secretion by human CD4(+) T cells: relevance to inflammatory bowel disease
por: Veenbergen, S, et al.
Publicado: (2019) -
Changes in Natural Foxp3(+)Treg but Not Mucosally-Imprinted CD62L(neg)CD38(+)Foxp3(+)Treg in the Circulation of Celiac Disease Patients
por: van Leeuwen, Marieke A., et al.
Publicado: (2013) -
Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis
por: Joosse, Maria E., et al.
Publicado: (2021) -
Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation
por: Nugteren, Sandrine, et al.
Publicado: (2022) -
Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+)CD11b(+) DCs in the intestinal lamina propria
por: Scott, Charlotte L, et al.
Publicado: (2014)