Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor

OBJECTIVE: To identify target antigens presented by human leukocyte antigen (HLA)–A*02:01 to the myelin-reactive human T-cell receptor (TCR) 2D1, which was originally isolated from a CD8+ T-cell clone recognizing proteolipid protein (PLP) in the context of HLA-A*03:01, we employed a new antigen sear...

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Detalles Bibliográficos
Autores principales: Rühl, Geraldine, Niedl, Anna G., Patronov, Atanas, Siewert, Katherina, Pinkert, Stefan, Kalemanov, Maria, Friese, Manuel A., Attfield, Kathrine E., Antes, Iris, Hohlfeld, Reinhard, Dornmair, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871805/
https://www.ncbi.nlm.nih.gov/pubmed/27231714
http://dx.doi.org/10.1212/NXI.0000000000000241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871805/
https://www.ncbi.nlm.nih.gov/pubmed/27231714
http://dx.doi.org/10.1212/NXI.0000000000000241

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