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Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor
OBJECTIVE: To identify target antigens presented by human leukocyte antigen (HLA)–A*02:01 to the myelin-reactive human T-cell receptor (TCR) 2D1, which was originally isolated from a CD8+ T-cell clone recognizing proteolipid protein (PLP) in the context of HLA-A*03:01, we employed a new antigen sear...
Autores principales: | Rühl, Geraldine, Niedl, Anna G., Patronov, Atanas, Siewert, Katherina, Pinkert, Stefan, Kalemanov, Maria, Friese, Manuel A., Attfield, Kathrine E., Antes, Iris, Hohlfeld, Reinhard, Dornmair, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871805/ https://www.ncbi.nlm.nih.gov/pubmed/27231714 http://dx.doi.org/10.1212/NXI.0000000000000241 |
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