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Functional Profiling of Human MeCP2 by Automated Data Comparison Analysis and Computerized Expression Pathway Modeling

OBJECTIVES: Methyl-CpG binding protein 2 (MeCP2) is a ubiquitous epigenetic factor that represses gene expression by modifying chromatin. Mutations in the MeCP2 gene cause Rett syndrome, a progressive neurodevelopmental disorder. Recent studies also have shown that MeCP2 plays a role in carcinogenes...

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Detalles Bibliográficos
Autores principales: Kim, Injoo, Lee, Shin Hae, Jeong, Jinwoo, Park, Jun Hyung, Yoo, Mi Ae, Kim, Cheol Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Medical Informatics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871842/
https://www.ncbi.nlm.nih.gov/pubmed/27200222
http://dx.doi.org/10.4258/hir.2016.22.2.120