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Long-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system
Visualization of chromosomal dynamics is important for understanding many fundamental intra-nuclear processes. Efficient and reliable live-cell multicolor labeling of chromosomal loci can realize this goal. However, the current methods are constrained mainly by insufficient labeling throughput, effi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872083/ https://www.ncbi.nlm.nih.gov/pubmed/26850639 http://dx.doi.org/10.1093/nar/gkw066 |