An RNA trapping mechanism in Alphavirus mRNA promotes ribosome stalling and translation initiation

During translation initiation, eukaryotic initiation factor 2 (eIF2) delivers the Met-tRNA to the 40S ribosomal subunit to locate the initiation codon (AUG(i)) of mRNA during the scanning process. Stress-induced eIF2 phosphorylation leads to a general blockade of translation initiation and represent...

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Detalles Bibliográficos
Autores principales: Toribio, René, Díaz-López, Irene, Boskovic, Jasminka, Ventoso, Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872096/
https://www.ncbi.nlm.nih.gov/pubmed/26984530
http://dx.doi.org/10.1093/nar/gkw172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872096/
https://www.ncbi.nlm.nih.gov/pubmed/26984530
http://dx.doi.org/10.1093/nar/gkw172

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