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DHX29 reduces leaky scanning through an upstream AUG codon regardless of its nucleotide context

During eukaryotic translation initiation, the 43S preinitiation complex (43S PIC), consisting of the 40S ribosomal subunit, eukaryotic initiation factors (eIFs) and initiator tRNA scans mRNA to find an appropriate start codon. Key roles in the accuracy of initiation codon selection belong to eIF1 an...

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Detalles Bibliográficos
Autores principales: Pisareva, Vera P., Pisarev, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872109/
https://www.ncbi.nlm.nih.gov/pubmed/27067542
http://dx.doi.org/10.1093/nar/gkw240