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DNA motifs determining the accuracy of repeat duplication during CRISPR adaptation in Haloarcula hispanica
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) acquire new spacers to generate adaptive immunity in prokaryotes. During spacer integration, the leader-preceded repeat is always accurately duplicated, leading to speculations of a repeat-length ruler. Here in Haloarcula hispanica,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872114/ https://www.ncbi.nlm.nih.gov/pubmed/27085805 http://dx.doi.org/10.1093/nar/gkw260 |