Cell-cell contact and matrix adhesion promote αSMA expression during TGFβ1-induced epithelial-myofibroblast transition via Notch and MRTF-A

During epithelial-mesenchymal transition (EMT) epithelial cells lose cell-cell adhesion, exhibit morphological changes, and upregulate the expression of cytoskeletal proteins. Previous studies have demonstrated that complete disruption of cell-cell contact can promote transforming growth factor (TGF...

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Detalles Bibliográficos
Autores principales: O’Connor, Joseph W., Mistry, Krunal, Detweiler, Dayne, Wang, Clayton, Gomez, Esther W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872162/
https://www.ncbi.nlm.nih.gov/pubmed/27194451
http://dx.doi.org/10.1038/srep26226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872162/
https://www.ncbi.nlm.nih.gov/pubmed/27194451
http://dx.doi.org/10.1038/srep26226

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