Targeting human respiratory syncytial virus transcription anti-termination factor M2-1 to inhibit in vivo viral replication

Human respiratory syncytial virus (hRSV) is a leading cause of acute lower respiratory tract infection in infants, elderly and immunocompromised individuals. To date, no specific antiviral drug is available to treat or prevent this disease. Here, we report that the Smoothened receptor (Smo) antagoni...

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Detalles Bibliográficos
Autores principales: Bailly, B., Richard, C.-A., Sharma, G., Wang, L., Johansen, L., Cao, J., Pendharkar, V., Sharma, D.-C., Galloux, M., Wang, Y., Cui, R., Zou, G., Guillon, P., von Itzstein, M., Eléouët, J.-F., Altmeyer, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872165/
https://www.ncbi.nlm.nih.gov/pubmed/27194388
http://dx.doi.org/10.1038/srep25806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872165/
https://www.ncbi.nlm.nih.gov/pubmed/27194388
http://dx.doi.org/10.1038/srep25806

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