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Targeting human respiratory syncytial virus transcription anti-termination factor M2-1 to inhibit in vivo viral replication
Human respiratory syncytial virus (hRSV) is a leading cause of acute lower respiratory tract infection in infants, elderly and immunocompromised individuals. To date, no specific antiviral drug is available to treat or prevent this disease. Here, we report that the Smoothened receptor (Smo) antagoni...
Autores principales: | Bailly, B., Richard, C.-A., Sharma, G., Wang, L., Johansen, L., Cao, J., Pendharkar, V., Sharma, D.-C., Galloux, M., Wang, Y., Cui, R., Zou, G., Guillon, P., von Itzstein, M., Eléouët, J.-F., Altmeyer, R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872165/ https://www.ncbi.nlm.nih.gov/pubmed/27194388 http://dx.doi.org/10.1038/srep25806 |
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