Targeting B-cell receptor signaling kinases in chronic lymphocytic leukemia: the promise of entospletinib

The B-cell receptor signaling pathway has emerged as an important therapeutic target in chronic lymphocytic leukemia and other B-cell malignancies. Novel agents have been developed targeting the signaling enzymes spleen tyrosine kinase (SYK), Bruton’s tyrosine kinase, and phosphoinositide 3-kinase d...

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Detalles Bibliográficos
Autores principales: Sharman, Jeff, Di Paolo, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872176/
https://www.ncbi.nlm.nih.gov/pubmed/27247756
http://dx.doi.org/10.1177/2040620716636542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872176/
https://www.ncbi.nlm.nih.gov/pubmed/27247756
http://dx.doi.org/10.1177/2040620716636542

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