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Neuromyelitis optica study model based on chronic infusion of autoantibodies in rat cerebrospinal fluid
BACKGROUND: Devic’s neuromyelitis optica (NMO) is an autoimmune astrocytopathy, associated with central nervous system inflammation, demyelination, and neuronal injury. Several studies confirmed that autoantibodies directed against aquaporin-4 (AQP4-IgG) are relevant in the pathogenesis of NMO, main...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872335/ https://www.ncbi.nlm.nih.gov/pubmed/27193196 http://dx.doi.org/10.1186/s12974-016-0577-8 |