Neuromyelitis optica study model based on chronic infusion of autoantibodies in rat cerebrospinal fluid

BACKGROUND: Devic’s neuromyelitis optica (NMO) is an autoimmune astrocytopathy, associated with central nervous system inflammation, demyelination, and neuronal injury. Several studies confirmed that autoantibodies directed against aquaporin-4 (AQP4-IgG) are relevant in the pathogenesis of NMO, main...

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Detalles Bibliográficos
Autores principales: Marignier, R., Ruiz, A., Cavagna, S., Nicole, A., Watrin, C., Touret, M., Parrot, S., Malleret, G., Peyron, C., Benetollo, C., Auvergnon, N., Vukusic, S., Giraudon, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872335/
https://www.ncbi.nlm.nih.gov/pubmed/27193196
http://dx.doi.org/10.1186/s12974-016-0577-8

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