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Overexpression of CTNND1 in hepatocellular carcinoma promotes carcinous characters through activation of Wnt/β-catenin signaling

BACKGROUND: Increasing evidence supports the association of CTNND1 with tumor development and progression. However, the mechanism and clinical significance of CTNND1 deregulation in hepatocellular carcinoma (HCC) remains unknown. In this study, we aim to investigate the role of CTNND1 in HCC. METHOD...

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Detalles Bibliográficos
Autores principales: Tang, Bo, Tang, Fang, Wang, Zhenran, Qi, Guangying, Liang, Xingsi, Li, Bo, Yuan, Shengguang, Liu, Jie, Yu, Shuiping, He, Songqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872337/
https://www.ncbi.nlm.nih.gov/pubmed/27193094
http://dx.doi.org/10.1186/s13046-016-0344-9