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Early life overfeeding impairs spatial memory performance by reducing microglial sensitivity to learning
BACKGROUND: Obesity can lead to cognitive dysfunction including poor performance in memory tasks. However, poor memory is not seen in all obese humans and takes several months to develop in animal models, indicating the adult brain is relatively resistant to obesity’s cognitive effects. We have seen...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872342/ https://www.ncbi.nlm.nih.gov/pubmed/27193330 http://dx.doi.org/10.1186/s12974-016-0578-7 |