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Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis

BACKGROUND: Alterations in genetic and epigenetic landscapes are known to contribute to the development of different types of cancer. However, the mechanistic links between transcription factors and the epigenome which coordinate the deregulation of gene networks during cell transformation are large...

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Detalles Bibliográficos
Autores principales: Malysheva, Valeriya, Mendoza-Parra, Marco Antonio, Saleem, Mohamed-Ashick M., Gronemeyer, Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872343/
https://www.ncbi.nlm.nih.gov/pubmed/27198694
http://dx.doi.org/10.1186/s13073-016-0310-3