Novel, primate-specific PDE10A isoform highlights gene expression complexity in human striatum with implications on the molecular pathology of bipolar disorder

Bipolar disorder is a highly heritable neuropsychiatric disorder affecting nearly 2.5% of the population. Prior genetic studies identified a panel of common and rare single-nucleotide polymorphisms associated with the disease that map to the first intron of the PDE10A gene. RNA sequencing of striata...

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Detalles Bibliográficos
Autores principales: MacMullen, C M, Vick, K, Pacifico, R, Fallahi-Sichani, M, Davis, R L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872433/
https://www.ncbi.nlm.nih.gov/pubmed/26905414
http://dx.doi.org/10.1038/tp.2016.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872433/
https://www.ncbi.nlm.nih.gov/pubmed/26905414
http://dx.doi.org/10.1038/tp.2016.3

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