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The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription

The G/C single-nucleotide polymorphism in the serotonin 1a receptor promoter, rs6295, has previously been linked with depression, suicide and antidepressant responsiveness. In vitro studies suggest that rs6295 may have functional effects on the expression of the serotonin 1a receptor gene (HTR1A) th...

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Detalles Bibliográficos
Autores principales: Donaldson, Z R, le Francois, B, Santos, T L, Almli, L M, Boldrini, M, Champagne, F A, Arango, V, Mann, J J, Stockmeier, C A, Galfalvy, H, Albert, P R, Ressler, K J, Hen, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872437/
https://www.ncbi.nlm.nih.gov/pubmed/26926882
http://dx.doi.org/10.1038/tp.2015.226