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MiR-582-5p/miR-590-5p targeted CREB1/CREB5–NF-κB signaling and caused opioid-induced immunosuppression in human monocytes

Chronic opioid abusers are more susceptible to bacterial and viral infections, but the molecular mechanism underlying opioid-induced immunosuppression is unknown. MicroRNAs (miRNAs) are emerging as key players in the control of biological processes, and may participate in immune regulation. In this...

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Detalles Bibliográficos
Autores principales: Long, X, Li, Y, Qiu, S, Liu, J, He, L, Peng, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872460/
https://www.ncbi.nlm.nih.gov/pubmed/26978739
http://dx.doi.org/10.1038/tp.2016.4