Abnormality in glutamine–glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study

Major depressive disorder (MDD), common in the elderly, is a risk factor for dementia. Abnormalities in glutamatergic neurotransmission via the N-methyl-d-aspartate receptor (NMDA-R) have a key role in the pathophysiology of depression. This study examined whether depression was associated with cere...

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Detalles Bibliográficos
Autores principales: Hashimoto, K, Bruno, D, Nierenberg, J, Marmar, C R, Zetterberg, H, Blennow, K, Pomara, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872461/
https://www.ncbi.nlm.nih.gov/pubmed/26926880
http://dx.doi.org/10.1038/tp.2016.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872461/
https://www.ncbi.nlm.nih.gov/pubmed/26926880
http://dx.doi.org/10.1038/tp.2016.8

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