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Abnormality in glutamine–glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study
Major depressive disorder (MDD), common in the elderly, is a risk factor for dementia. Abnormalities in glutamatergic neurotransmission via the N-methyl-d-aspartate receptor (NMDA-R) have a key role in the pathophysiology of depression. This study examined whether depression was associated with cere...
Autores principales: | Hashimoto, K, Bruno, D, Nierenberg, J, Marmar, C R, Zetterberg, H, Blennow, K, Pomara, N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872461/ https://www.ncbi.nlm.nih.gov/pubmed/26926880 http://dx.doi.org/10.1038/tp.2016.8 |
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