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Development of antithrombotic nanoconjugate blocking integrin α2β1-collagen interactions

An antithrombotic nanoconjugate was designed in which a designed biomimetic peptide LWWNSYY was immobilized to the surface of poly(glycidyl methacrylate) nanoparticles (PGMA NPs). Our previous work has demonstrated LWWNSYY to be an effective inhibitor of integrin α2β1-collagen interaction and subseq...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Zhang, Lin, Zhang, Youcai, Sun, Na, Jiang, Shaoyi, Fujihara, Timothy J., Sun, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872532/
https://www.ncbi.nlm.nih.gov/pubmed/27195826
http://dx.doi.org/10.1038/srep26292