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Development of antithrombotic nanoconjugate blocking integrin α2β1-collagen interactions
An antithrombotic nanoconjugate was designed in which a designed biomimetic peptide LWWNSYY was immobilized to the surface of poly(glycidyl methacrylate) nanoparticles (PGMA NPs). Our previous work has demonstrated LWWNSYY to be an effective inhibitor of integrin α2β1-collagen interaction and subseq...
Autores principales: | Zhang, Chao, Zhang, Lin, Zhang, Youcai, Sun, Na, Jiang, Shaoyi, Fujihara, Timothy J., Sun, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872532/ https://www.ncbi.nlm.nih.gov/pubmed/27195826 http://dx.doi.org/10.1038/srep26292 |
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