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Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes

In the heart compartmentalisation of cAMP/protein kinase A (PKA) signalling is necessary to achieve a specific functional outcome in response to different hormonal stimuli. Chronic exposure to catecholamines is known to be detrimental to the heart and disrupted compartmentalisation of cAMP signallin...

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Detalles Bibliográficos
Autores principales: Fields, Laura A., Koschinski, Andreas, Zaccolo, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872538/
https://www.ncbi.nlm.nih.gov/pubmed/26475678
http://dx.doi.org/10.1016/j.cellsig.2015.10.003