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Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes
In the heart compartmentalisation of cAMP/protein kinase A (PKA) signalling is necessary to achieve a specific functional outcome in response to different hormonal stimuli. Chronic exposure to catecholamines is known to be detrimental to the heart and disrupted compartmentalisation of cAMP signallin...
Autores principales: | Fields, Laura A., Koschinski, Andreas, Zaccolo, Manuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872538/ https://www.ncbi.nlm.nih.gov/pubmed/26475678 http://dx.doi.org/10.1016/j.cellsig.2015.10.003 |
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