Cargando…
An efficient algorithm to identify the optimal one-bit perturbation based on the basin-of-state size of Boolean networks
Boolean networks are widely used to model gene regulatory networks and to design therapeutic intervention strategies to affect the long-term behavior of systems. In this paper, we investigate the less-studied one-bit perturbation, which falls under the category of structural intervention. Previous w...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872544/ https://www.ncbi.nlm.nih.gov/pubmed/27196530 http://dx.doi.org/10.1038/srep26247 |