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Coevolution of RAC Small GTPases and their Regulators GEF Proteins
RAC proteins are small GTPases involved in important cellular processes in eukaryotes, and their deregulation may contribute to cancer. Activation of RAC proteins is regulated by DOCK and DBL protein families of guanine nucleotide exchange factors (GEFs). Although DOCK and DBL proteins act as GEFs o...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Libertas Academica
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872645/ https://www.ncbi.nlm.nih.gov/pubmed/27226705 http://dx.doi.org/10.4137/EBO.S38031 |