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Coevolution of RAC Small GTPases and their Regulators GEF Proteins

RAC proteins are small GTPases involved in important cellular processes in eukaryotes, and their deregulation may contribute to cancer. Activation of RAC proteins is regulated by DOCK and DBL protein families of guanine nucleotide exchange factors (GEFs). Although DOCK and DBL proteins act as GEFs o...

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Detalles Bibliográficos
Autor principal: Jiménez-Sánchez, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872645/
https://www.ncbi.nlm.nih.gov/pubmed/27226705
http://dx.doi.org/10.4137/EBO.S38031