PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia

Hypoxia-inducible factors (HIFs) control the transcription of genes that are crucial for the pathogenesis of cancer and other human diseases. The transcriptional activity of HIFs is rapidly increased upon exposure to hypoxia, but expression of some HIF target genes decreases during prolonged hypoxia...

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Detalles Bibliográficos
Autores principales: Luo, Weibo, Chen, Ivan, Chen, Yan, Alkam, Duah, Wang, Yingfei, Semenza, Gregg L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872721/
https://www.ncbi.nlm.nih.gov/pubmed/26837221
http://dx.doi.org/10.18632/oncotarget.7142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872721/
https://www.ncbi.nlm.nih.gov/pubmed/26837221
http://dx.doi.org/10.18632/oncotarget.7142

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