Human melanoma immunotherapy using tumor antigen-specific T cells generated in humanized mice

A major factor hindering the exploration of adoptive immunotherapy in preclinical settings is the limited availability of tumor-reactive human T cells. Here we developed a humanized mouse model that permits large-scale production of human T cells expressing the engineered melanoma antigen MART-1-spe...

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Detalles Bibliográficos
Autores principales: Hu, Zheng, Xia, Jinxing, Fan, Wei, Wargo, Jennifer, Yang, Yong-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872726/
https://www.ncbi.nlm.nih.gov/pubmed/26824989
http://dx.doi.org/10.18632/oncotarget.7044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872726/
https://www.ncbi.nlm.nih.gov/pubmed/26824989
http://dx.doi.org/10.18632/oncotarget.7044

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