Integrated genomic analyses identify frequent gene fusion events and VHL inactivation in gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. We sequenced nine exomes and transcriptomes, and two genomes of GISTs for integrated analyses. We detected 306 somatic variants in nine GISTs and recurrent protein-altering mutations in 29 g...

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Detalles Bibliográficos
Autores principales: Kang, Guhyun, Yun, Hongseok, Sun, Choong-Hyun, Park, Inho, Lee, Seungmook, Kwon, Jekeun, Do, Ingu, Hong, Min Eui, Van Vrancken, Michael, Lee, Jeeyun, Park, Joon Oh, Cho, Jeonghee, Kim, Kyoung-Mee, Sohn, Tae Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872731/
https://www.ncbi.nlm.nih.gov/pubmed/25987131
http://dx.doi.org/10.18632/oncotarget.3731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872731/
https://www.ncbi.nlm.nih.gov/pubmed/25987131
http://dx.doi.org/10.18632/oncotarget.3731

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