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MiRNAs and piRNAs from bone marrow mesenchymal stem cell extracellular vesicles induce cell survival and inhibit cell differentiation of cord blood hematopoietic stem cells: a new insight in transplantation

Hematopoietic stem cells (HSC), including umbilical cord blood CD34+ stem cells (UCB-CD34+), are used for the treatment of several diseases. Although different studies suggest that bone marrow mesenchymal stem cells (BM-MSC) support hematopoiesis, the exact mechanism remains unclear. Recently, extra...

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Detalles Bibliográficos
Autores principales: De Luca, Luciana, Trino, Stefania, Laurenzana, Ilaria, Simeon, Vittorio, Calice, Giovanni, Raimondo, Stefania, Podestà, Marina, Santodirocco, Michele, Di Mauro, Lazzaro, La Rocca, Francesco, Caivano, Antonella, Morano, Annalisa, Frassoni, Francesco, Cilloni, Daniela, Del Vecchio, Luigi, Musto, Pellegrino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872742/
https://www.ncbi.nlm.nih.gov/pubmed/26760763
http://dx.doi.org/10.18632/oncotarget.6791