NG2 proteoglycan as a pericyte target for anticancer therapy by tumor vessel infarction with retargeted tissue factor

tTF-TAA and tTF-LTL are fusion proteins consisting of the extracellular domain of tissue factor (TF) and the peptides TAASGVRSMH and LTLRWVGLMS, respectively. These peptides represent ligands of NG2, a surface proteoglycan expressed on angiogenic pericytes and some tumor cells. Here we have expresse...

Descripción completa

Detalles Bibliográficos
Autores principales: Brand, Caroline, Schliemann, Christoph, Ring, Janine, Kessler, Torsten, Bäumer, Sebastian, Angenendt, Linus, Mantke, Verena, Ross, Rebecca, Hintelmann, Heike, Spieker, Tilmann, Wardelmann, Eva, Mesters, Rolf M., Berdel, Wolfgang E., Schwöppe, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872748/
https://www.ncbi.nlm.nih.gov/pubmed/26735180
http://dx.doi.org/10.18632/oncotarget.6725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872748/
https://www.ncbi.nlm.nih.gov/pubmed/26735180
http://dx.doi.org/10.18632/oncotarget.6725

Ejemplares similares