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Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors

B7 family proteins are important immune response regulators, and can mediate oncogenic signaling and cancer development. We have used human triple-negative breast cancer cell lines with different expression levels of B7-H3 to evaluate its effects on the sensitivity to 22 different anticancer compoun...

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Detalles Bibliográficos
Autores principales: Nunes-Xavier, Caroline E., Karlsen, Karine Flem, Tekle, Christina, Pedersen, Cathrine, Øyjord, Tove, Hongisto, Vesa, Nesland, Jahn M., Tan, Ming, Sahlberg, Kristine Kleivi, Fodstad, Øystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872756/
https://www.ncbi.nlm.nih.gov/pubmed/26771843
http://dx.doi.org/10.18632/oncotarget.6902